BIOLOGY

VCE Biology Units 1–4 Comprehensive Concept List
Units 1 & 2 (Year 11) – Foundation Topics
Unit 1: How Do Organisms Regulate Their Functions?
Cells and Cell Structure
Prokaryotic vs. eukaryotic cells
Cell organelles and their functions
Plasma membrane structure and function (fluid mosaic model)
Passive and active transport (diffusion, osmosis, facilitated diffusion, endocytosis, exocytosis)
Biochemical Processes
Enzymes and factors affecting enzyme activity
Photosynthesis (light-dependent and light-independent reactions)
Cellular respiration (aerobic and anaerobic)
Homeostasis and Regulation
Negative and positive feedback mechanisms
Nervous and endocrine system regulation
Osmoregulation and thermoregulation
Unit 2: How Does Inheritance Impact Diversity?
Reproduction and Cell Division
Mitosis and the cell cycle
Meiosis and genetic variation
Asexual vs. sexual reproduction
Genetics and Inheritance
DNA structure and replication
Genes, alleles, and genetic variation
Mendelian genetics (dominant, recessive, co-dominance, incomplete dominance)
Punnett squares and pedigree analysis
Polygenic inheritance and epigenetics
Evolution and Natural Selection
Darwinian evolution and natural selection
Genetic drift, gene flow, and mutations
Speciation and evolutionary changes
Fossil record and evidence for evolution
Units 3 & 4 (Year 12) – Advanced Topics
Unit 3: How Do Cells Maintain Life?
Biochemistry and Cellular Processes
Structure and function of biomacromolecules (proteins, nucleic acids, carbohydrates, lipids)
Transcription and translation (gene expression)
Enzymes and biochemical pathways
Photosynthesis and cellular respiration
Signalling and Cellular Communication
Types of cellular signals (autocrine, paracrine, endocrine)
Signal transduction pathways
Apoptosis and programmed cell death
Immunology
Innate vs. adaptive immunity
Structure and function of antibodies
The role of B cells, T cells, and antigen-presenting cells
Vaccination and immune memory
Unit 4: How Does Life Change and Respond to Challenges?
Molecular Genetics and Heredity
Mutations and their effects on genes
Genetic screening and testing
DNA manipulation (CRISPR, gene cloning, recombinant DNA)
Polymerase Chain Reaction (PCR) and gel electrophoresis
Evolution and Speciation
Phylogenetics and evolutionary relationships
Molecular clock hypothesis
Human evolution and fossil evidence
Biotechnology and Bioethics
Genetic modification and transgenic organisms
Stem cells and regenerative medicine
Bioethical considerations in genetic technology